Searching for the right medical office space in Los Angeles is no small feat. The city’s vast sprawl, high demand, and diverse neighborhoods mean that one-size-fits-all solutions simply don’t work. From the polished streets of Beverly Hills to the family-friendly vibe of Brentwood, choosing the right location could significantly impact your patient flow, business success, and day-to-day satisfaction as a healthcare provider.

In this in-depth 2025 guide, we’ll walk you through the top medical office locations in Los Angeles, breaking down lease options, neighborhood advantages, patient demographics, and practical amenities. Whether you’re launching a new practice or expanding an existing one, this expert-curated guide will help you make informed decisions that align with your goals.

Why Location Matters for Medical Practices

Where you open your medical office can shape your clientele, brand image, and long-term growth. Los Angeles is a mosaic of unique neighborhoods, each with its own healthcare demands and patient expectations. For instance, Beverly Hills patients often seek high-end cosmetic or concierge services, while Brentwood may be more suited to pediatricians and general practitioners catering to families.

Patient convenience also plays a vital role. Offices located near public transit, with easy parking and walkable access to pharmacies or restaurants, tend to attract more loyal patients. If your practice is centered around a specific specialty or demographic, understanding these nuances will help you thrive.

Flexible Leasing: The Residen Advantage

At Residen, we offer flexible leasing options in some of L.A.’s most sought-after neighborhoods, including Beverly Hills and Brentwood. Whether you’re looking for short-term rentals to test the market or long-term commitments to anchor your practice, Residen’s no-minimum leasing model provides unmatched adaptability.

Why Choose Residen?

• Prime Locations: Highly accessible buildings in high-demand neighborhoods.

• Furnished Units: Move-in ready, beautifully designed office spaces.

• Customizable Suites: Adaptable layouts for a variety of medical specialties.

• Parking & Transit Access: Ample on-site parking and proximity to public transportation.

• Scalable Leases: Grow with your patient base—without being locked into lengthy terms.

Top Neighborhoods for Medical Office Space in Los Angeles

Let’s dive into the most strategic areas for medical offices across Los Angeles, highlighting their unique appeal and suitability for different types of practices.

Beverly Hills: High-End Healthcare Hub

• Ideal For: Cosmetic surgeons, dermatologists, concierge medicine, plastic surgery, wellness clinics

• Why It Works: Beverly Hills is synonymous with luxury, attracting patients both locally and globally. Offices along Wilshire Blvd and Rodeo Drive are surrounded by high-net-worth individuals seeking premier healthcare experiences.

• Considerations: Premium rents, but potential for substantial ROI due to high service pricing and affluent clientele.

• Amenities: Luxury buildings, valet parking, nearby luxury hotels and pharmacies.

Brentwood: Family-Friendly and Community-Centered

• Ideal For: General practitioners, pediatricians, internal medicine, family medicine

• Why It Works: Brentwood offers a consistent, family-oriented patient base. Offices on San Vicente Blvd are easily accessible and embedded in a tight-knit community.

• Considerations: Moderate rental prices, ideal for steady, long-term patient relationships.

• Amenities: Parks, retail, schools, and community centers nearby.

Culver City: Affordable and Centrally Located

• Ideal For: New practices, mixed specialties, wellness clinics

• Why It Works: Diverse population and central location with growing commercial infrastructure. It’s a great stepping stone into the LA market.

• Considerations: Lower costs, but competition from urgent care and other emerging clinics.

• Amenities: Near public transport, mixed-use developments, and residential areas.

Downtown Los Angeles (DTLA): Urban & High-Visibility

• Ideal For: Specialists, urgent care, internal medicine, telehealth hybrid setups

• Why It Works: High foot traffic and close to major hospitals and business hubs.

• Considerations: Office spaces vary widely in size and cost. High demand can limit options.

• Amenities: Close to hospitals, pharmacies, business centers, and public transport.

San Fernando Valley (Van Nuys, Encino, Woodland Hills, Westlake)

• Ideal For: Multi-specialty clinics, dental offices, family practice

• Why It Works: Large, suburban population with affordable rents and high visibility along Ventura Blvd.

• Considerations: Ideal for volume-based practices and growing patient bases.

• Amenities: Easy freeway access, spacious parking lots, large office footprints.

Glendale

• Ideal For: Generalists, OB/GYN, mental health services

• Why It Works: Growing medical community and access to both L.A. and Pasadena markets. Glendale offers mid-range pricing with high patient diversity.

• Amenities: Modern buildings, ample parking, shopping centers nearby.

Santa Monica

• Ideal For: Wellness clinics, holistic medicine, physical therapy

• Why It Works: Attracts patients focused on health, fitness, and alternative treatments. A great location for integrating lifestyle services.

• Considerations: Higher rent, but ideal for premium wellness brands.

• Amenities: Coastal access, luxury gyms, holistic markets.

Long Beach

• Ideal For: Family medicine, specialty care, urgent care

• Why It Works: Coastal city with strong community ties and access to Orange County patients.

• Considerations: Lower rent, growing healthcare infrastructure.

• Amenities: Coastal lifestyle, residential appeal, schools, and transportation hubs.

Short-Term vs. Long-Term Leasing: Which One is Right for You?

Short-Term Leasing

• Great for startups or satellite offices.

• Flexibility to test new markets or services.

• Lower financial risk with no long-term commitment.

• Ideal for practices introducing telemedicine or part-time services.

Long-Term Leasing

• Better suited for established practices with stable patient bases.

• Reduced monthly rent and predictable operational costs.

• Suitable for physicians investing in heavy medical equipment or renovations.

Residen offers both options, including hourly, daily, and month-to-month rentals tailored for modern medical professionals.

Cost Breakdown by Neighborhood

Here’s a snapshot of average monthly leasing costs per square foot (2025 estimates):